Publications

Pre-Clinical Data

Kulstad EB, Courtney DM, Waller D. “Induction of Therapeutic Hypothermia via the Esophagus: a Proof of Concept Study”. World Journal of Emergency Medicine. 2012, 3(2):118-122.

Vaicys V, Eason A, Schieber JD, Kulstad EB. “Therapeutic Hypothermia Induction via an Esophageal Route–a Computer Simulation”. American Journal of Emergency Medicine. 2012, 30(6):932-935.

Kulstad E, Metzger AK, Courtney DM, Rees J, Shanley P, Matsuura T, McKnite S, Lurie K. “Induction, Maintenance, and Reversal of Therapeutic Hypothermia with an Esophageal Heat Transfer Device”. Resuscitation. 2013, 84(11):1619-1624.

Kulstad EB, Naiman M, Shanley P, Garrett F, Haryu T, Waller D, Azarafrooz F, Courtney DM. “Temperature Modulation with an Esophageal Heat Transfer Device – a Pediatric Swine Model Study”. BMC Anesthesiology. 2015, 15:16.

Clinical Data

Markota A, Fluher J, Balazic P, Kit B, Sinkovic A. “Therapeutic Hypothermia with Esophageal Heat Transfer Device”. Resuscitation. 2015, 96:138.

Markota A, Kit B, Fluher J, Sinkovic A. “Use of an Oesophageal Heat Transfer Device in Therapeutic Hypothermia”. Resuscitation. 2015, 89:e1-2.

Markota A, Fluher J, Kit B, Balažič P, Sinkovič A. “The Introduction of an Esophageal Heat Transfer Device into a Therapeutic Hypothermia Protocol: a Prospective Evaluation”. The American Journal of Emergency Medicine. 2016, 34(4):741-745.

Hegazy A, Lapierre D, Althenayan E. “Targeted Temperature Management after Cardiac Arrest and Fever Control with an Esophageal Cooling Device”. Critical Care. 2015, 19(Suppl 1):P424.

Hegazy AF, Lapierre DM, Butler R, Althenayan E. “Temperature Control in Critically Ill Patients with a Novel Esophageal Cooling Device: a Case Series. BMC Anesthesiology. 2015, 15(1):152.

Badjatia N, Khan I, Haymore J, Melinosky C, Bautista MA, Chang WT, Parikh G, Motta M. “Novel Esophageal Cooling Device For Therapeutic Normothermia”. 6th International Hypothermia and Temperature Management Symposium, September 12–14, 2016 Philadelphia, Pennsylvania.

Markota A, Košir AS, Balažič P, Živko I, Sinkovič A. “A Novel Esophageal Heat Transfer Device for Temperature Management in an Adult Patient with Severe Meningitis”. The Journal of Emergency Medicine. In Press, e-Pub ahead of print.

Zivko I, Balazic P, Markota A, Sinkovic A. “Temperature Management in an Adult Patient with Severe Meningitis Using a Novel Esophageal Heat Transfer Device”. 12th Emirates Critical Care Conference. Dubai, UAE; 2016.

Williams D, Leslie G, kyriazis D, O’Donovan B, Bowes J, Dingley J. “Use of an Esophageal Heat Exchanger to Maintain Core Temperature During Burn Excisions and to Attenuate Pyrexia On the Burns Intensive Care Unit”. Case Reports in Anesthesiology. vol. 2016, Article ID 7306341, 6 pages, 2016. doi:10.1155/2016/7306341.

Recent Reviews and Other References to the ECD

Tommasi E, Lazzeri C, Bernardo P, Sori A, Chiostri M, Gensini GF, Valente S. “Cooling Techniques in Mild Hypothermia after Cardiac Arrest”. Journal Cardiovascular Medicine (Hagerstown) 2014.

Vaity C, Al-Subaie N, Cecconi M. “Cooling Techniques for Targeted Temperature Management Post-Cardiac Arrest”. Critical Care. 2015, 19(1):103.

Omi E, Kulstad E. “An Additional Method for the Prevention of Hypothermia in Severely Injured Trauma Patients”. Critical Care. 2016, 20(1):198.

Naiman M, Shanley P, Garrett F, Kulstad E. “Evaluation of Advanced Cooling Therapy’s Esophageal Cooling Device for Core Temperature Control. Expert Reviews of Medical Devices. 2016, 13(5):423-433.

Recent Presentations

“Temperature Management in Critical Care and Burn Patients using an Esophageal Heat Transfer Device”. Podium presentation during the 2016 Military Health System Research Symposium, August 15-18, 2016. Orlando, Florida.

Novel Esophageal Cooling Device for Therapeutic Normothermia”. Abstract published in Therapeutic Hypothermia and Temperature Management Journal (Aug 2016, 6(3): 156, #28) and presented during the 6th Annual International Hypothermia and Temperature Management Symposium. September 12-14, 2016. Philadelphia, Pennsylvania.

Targeted Temperature Maintenance using an Esophageal Heat Transfer Device”. Abstract published in Therapeutic Hypothermia and Temperature Management Journal (Aug 2016, 6(3): 155, #24) and presented during the 6th International Hypothermia & Temperature Management Symposium, September 12-14, 2016. Philadelphia, Pennsylvania.

Novel Esophageal Cooling Device for Therapeutic Normothermia”. Poster presented during the 14th Annual Neurocritical Care Society Meeting, September 15-18, 2016. National Harbor, Maryland.

Temperature Management and Fever Avoidance in Critical Care Patients using an Esophageal Heat Transfer Device”. Poster presented during the 14th Annual Neurocritical Care Society Meeting, September 15-18, 2016. National Harbor, Maryland.

Ongoing Clinical Trials in Progress

Temperature Control with an Esophageal Cooling Device in Post Cardiac Arrest Patients (E-Chill) – NCT02387775

Evaluating Heat Transfer with the Esophageal Cooling Device – NCT02743884

Prospective, Interventional Study Evaluating the Feasibility and Safety of the Esophageal Cooling Device in Traumatic Brain Injury – NCT02420639

Esophageal Temperature Management after Cardiac Arrest (THE-COOL) – NCT02327871

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